dna repair

The gene sirtuin 6 (SIRT6) is responsible for more efficient DNA repair in species with longer lifespans, new research from the University of Rochester indicates. The finding sheds light on new targets for anti-aging interventions and could help prevent age-related diseases. As humans and other mammals grow older, their DNA is increasingly prone to breaks… Read more

Many chemotherapy drugs work by damaging cancer cells’ DNA so severely that the cells are forced to commit cellular suicide. However, these drugs don’t work for all patients. If cells can repair the DNA damage, they may survive treatment. MIT researchers have now developed a way to test cells’ ability to perform several different types… Read more

UV light damages DNA. But Ludwig Maximilian University of Munich researchers now show that it can also mediate non-enzymatic repair of one type of damage, albeit in a specific context. This effect may have played vital role in early evolution of living systems. The ultraviolet wavelength of sunlight triggers photochemical reactions in the DNA molecules… Read more

This year’s Nobel Prize in chemistry was given to three scientists who each focused on one piece of the DNA repair puzzle. Now a new study reports the discovery of a new class of DNA repair enzyme. When the structure of DNA was first discovered, scientists imagined it to be extremely chemically stable, which allowed… Read more