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SIRT6 Gene Behind More Efficient DNA Repair In Longer Living Species

The gene sirtuin 6 (SIRT6) is responsible for more efficient DNA repair in species with longer lifespans, new research from the University of Rochester indicates. The finding sheds light on new targets for anti-aging interventions and could help prevent age-related diseases. As humans and other mammals grow older, their DNA is increasingly prone to breaks, […]

Measuring DNA Repair Capability Can Reveal Tumors’ Drug Sensitivity

Many chemotherapy drugs work by damaging cancer cells’ DNA so severely that the cells are forced to commit cellular suicide. However, these drugs don’t work for all patients. If cells can repair the DNA damage, they may survive treatment. MIT researchers have now developed a way to test cells’ ability to perform several different types […]