cystic fibrosis

Genome editing has been used to demonstrate the efficacy of CRISPR-Cas to treat the genetic problem that causes cystic fibrosis. The approach adopted by the research team opens new perspectives in the treatment of the genetic disease for which no cure is currently available. The disease is caused by a mutation of the gene that… Read more

Cystic fibrosis is a life-threatening genetic disease which affects lung function through the build-up of a difficult to clear mucus. This occurs due to a gene mutation, and the mucus which builds up is an ideal environment for bacterial infections, which cause inflammation and structural damage to the lungs. Delivery of antibiotics is crucial to… Read more

Antibiotic-resistant Pseudomonas infections in cystic fibrosis patients show predictable sensitivities to other classes of antibiotics. This could lead to new ways of optimizing treatments for chronic infections, a new study from the Novo Nordisk Foundation Center for Biosustainability at the Technical University of Denmark suggests. “Our discovery of widespread antibiotic sensitivities in the multidrug-resistant pathogen… Read more

Promising research towards a possible stem cell treatment for several lung conditions has been developed by scientists from the UNC School of Medicine and North Carolina State University. The conditions include idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD), and cystic fibrosis — often-fatal conditions that affect tens of millions of Americans. The team… Read more

A new material that inhibits biofilm formation of the virulent superbug Pseudomonas aeruginosa has been created by Colorado State University researchers. The material could form the basis for a new kind of antibacterial surface that prevents infections and reduces our reliance on antibiotics. Bella Neufeld, the first author and graduate student who led the research… Read more