colon cancer

The development of an aggressive, early-onset form of colon cancer may come down to a single missing iron atom in a key DNA repair protein, according to new research. The findings reveal how a mutation in the MUTYH protein prevents it from doing its job repairing damaged DNA. The study also shows for the first… Read more

Modifying the shape of IRAK-M, a protein that controls inflammation, can significantly reduce the clinical progression of inflammatory bowel disease and colon cancer in pre-clinical animal models, Virginia Tech researchers have found. Interleukin receptor associated kinase M (IRAK-M), the altered protein, causes the immune system to become supercharged, clearing out the bacteria before they can… Read more

New research has found a subset of our immune cells, named regulatory T cells, that are abundant in the tumor microenvironment and are particularly good at suppressing the anticancer immune response. In two independent studies, published in Immunity, scientists describe the distinct features and differences in molecules expressed by regulatory T cells inside of human… Read more

Combining two plant compounds that have medicinal properties, curcumin and silymarin, holds promise in treating colon cancer, according to new research from Saint Louis University. Curcumin is the active ingredient in the spice turmeric, which is present in spicy curry dishes. Silymarin is a component of milk thistle, which has been used to treat liver… Read more

A genetic blood test that identifies colon cancer related DNA can aid in predicting recurrence of the disease in certain patients. If the findings are verified in further research, the test could eventually help clinicians decide which patients need additional treatment after surgery for stage 2 cancer, according to researchers. Stage 2 tumors, typically are… Read more