Blood Tfr Cells Are Increased In Sjögren Syndrome

Patients with Sjögren syndrome have a significant increase in a specific immune cell type called T follicular regulatory cells (Tfr), a team from Instituto de Medicina Molecular Lisboa has found. These cells are usually found in lymphoid tissues, where they regulate antibody production. It was a surprise to find an…Continue readingBlood Tfr Cells Are Increased In Sjögren Syndrome

Tie2 On Pericytes Drives Angiogenesis And Vessel Maturation

Pericytes exhibit a receptor molecule called Tie2 on their surfaces, German Cancer Research Center scientists have discovered. The finding may help identify further therapy targets in order to prevent vessel formation in cancer more effectively. Cancer cells have an enormous need for oxygen and nutrients. Therefore, growing tumors rely on…Continue readingTie2 On Pericytes Drives Angiogenesis And Vessel Maturation

Gut Microbiome Influences Brain Blood Vessel Lesions

Bacteria in the gut can influence the structure of the brain’s blood vessels, and may be responsible for producing cerebral cavernous malformations, new research suggests. The study adds to the emerging concept connecting intestinal microbes and disorders of the nervous system. Cerebral cavernous malformations (CCMs) are clusters of dilated, thin-walled…Continue readingGut Microbiome Influences Brain Blood Vessel Lesions

New Glucose Responsive Insulin Delivery System With Red Blood Cells

A new technique that uses modified insulin and red blood cells to create a glucose-responsive “smart” insulin delivery system has been developed by researchers from North Carolina State University and the University of North Carolina at Chapel Hill. The new technique effectively reduced blood sugar levels for 48 hours in…Continue readingNew Glucose Responsive Insulin Delivery System With Red Blood Cells

Intravasation Can Begin Early During Tumor Development

Invasive tumors can begin intravasation, the sending out of tumor cells, far earlier than previously thought, according to a new study from The Scripps Research Institute. These escaping cells, which can enter the bloodstream before the primary tumor is detected, may seed secondary tumors that don’t show up for years.…Continue readingIntravasation Can Begin Early During Tumor Development

Extracellular Phosphoproteins Could Lead To Cancer Blood Test

A series of of proteins in blood plasma have been identified that, when elevated, signify the presence of cancer. The findings mean doctors may soon be able to detect and monitor cancer with a simple blood test, reducing or eliminating the need for more invasive procedures. While the work, that…Continue readingExtracellular Phosphoproteins Could Lead To Cancer Blood Test

Blood Biomarker Patterns That Predict Healthy Aging Identified

A set of biomarker signatures that suggest how well a person is aging and the risk for aging-related diseases has been identified by researchers at Boston University. The finding opens the door to a molecular-based definition of aging that uses information from multiple biomarkers to create signatures associated with different…Continue readingBlood Biomarker Patterns That Predict Healthy Aging Identified