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Blood-brain Barrier Breakdown Early Driver Of Dementia

Brain capillary damage forecasts early onset of Alzheimer’s disease, as it signals cognitive impairment before the hallmark toxic proteins amyloid and tau appear, new research from University of Southern California shows. The findings could help with earlier diagnosis and suggest new targets for drugs that could slow down or prevent the onset of the disease. […]

Saving The Brain With A New Nerve Agent Antidote

Terror on a Tokyo subway, 1995; attacks on Syrian civilians, 2013 and 2017; assassinations in an airport in Kuala Lumpur, 2017; attempted assassination in London, 2018. Tremors, foaming at the mouth, seizures, respiratory shutdown, sometimes death. What do these events have in common? Poisoning via a nerve agent – a chemical warfare substance that disrupts […]

How Acute Lymphoblastic Leukemia Invades The Central Nervous System

Acute lymphoblastic leukemia infiltrates the central nervous system not by breaching the blood-brain barrier, but by evading the barrier altogether, a research team led by Duke Cancer Institute scientists has found. A deadly feature of acute lymphoblastic leukemia (ALL) is its invasion of the central nervous system. ALL in the central nervous system is very […]