blood-brain barrier

Drugs that quell inflammation in the brain could slow or even reverse the cognitive decline that comes with age. Senile mice given one such drug had fewer signs of brain inflammation and were better able to learn new tasks, becoming almost as adept as mice half their age. “We tend to think about the aged… Read more

Brain capillary damage forecasts early onset of Alzheimer’s disease, as it signals cognitive impairment before the hallmark toxic proteins amyloid and tau appear, new research from University of Southern California shows. The findings could help with earlier diagnosis and suggest new targets for drugs that could slow down or prevent the onset of the disease… Read more

A new strategy to overcome one of the main obstacles in the treatment of brain cancer — access to the tumor – has been developed by an international team led by researchers at Baylor College of Medicine. Under the influence of cancer, the blood-brain barrier diverts immune T cells that attempt to enter the brain… Read more

Terror on a Tokyo subway, 1995; attacks on Syrian civilians, 2013 and 2017; assassinations in an airport in Kuala Lumpur, 2017; attempted assassination in London, 2018. Tremors, foaming at the mouth, seizures, respiratory shutdown, sometimes death. What do these events have in common? Poisoning via a nerve agent – a chemical warfare substance that disrupts… Read more

Acute lymphoblastic leukemia infiltrates the central nervous system not by breaching the blood-brain barrier, but by evading the barrier altogether, a research team led by Duke Cancer Institute scientists has found. A deadly feature of acute lymphoblastic leukemia (ALL) is its invasion of the central nervous system. ALL in the central nervous system is very… Read more