Vaccine Protection Against Congenital Zika Virus Infection

A new study in mice shows that females vaccinated before pregnancy and infected with Zika virus while pregnant bear pups who show no trace of the virus. The findings offer the first evidence that an effective vaccine administered prior to pregnancy can protect vulnerable fetuses from Zika infection and resulting…Continue readingVaccine Protection Against Congenital Zika Virus Infection

Alcohol Drinking During Pregnancy May Have Transgenerational Effects

Drinking alcohol during pregnancy will not only a mother’s unborn child, but may also impact brain development and lead to adverse outcomes in her future grand- and even great-grandchildren, reports a new study from the University of California, Riverside. The Centers for Disease Control and Prevention (CDC) has issued numerous…Continue readingAlcohol Drinking During Pregnancy May Have Transgenerational Effects

Antibodies May Block Transmission Of Congenital Cytomegalovirus

A way to protect fetuses from cytomegalovirus, or CMV has been identified in new Duke University research with monkeys. CMV can cause many of the same brain and developmental impairments as the Zika virus. One of only a handful known to be transmitted through the mother’s placenta to a fetus,…Continue readingAntibodies May Block Transmission Of Congenital Cytomegalovirus

How Congenital Cytomegalovirus Tricks The Immune System

Scientists from Cardiff University think they now know why congenital cytomegalovirus (CMV) is so effective at evading the immune system. The discovery could help treat the virus that is responsible for 1,000 birth defects a year in the UK alone. The findings show how a large number of CMV genes…Continue readingHow Congenital Cytomegalovirus Tricks The Immune System

Treacher Collins Syndrome: Three Genetic Mutations Identified As Cause

Scientists have reported a detailed description of how function-impairing mutations in polr1c and polr1d genes cause Treacher Collins syndrome (TCS). TCS is a rare congenital craniofacial development disorder that affects an estimated one in 50,000 live births. These findings reveal that a unifying cellular and biochemical mechanism underlies the etiology…Continue readingTreacher Collins Syndrome: Three Genetic Mutations Identified As Cause

Pregabalin During Pregnancy May Be Linked To Birth Defects

A drug commonly used to treat epilepsy, pain, anxiety and other brain health disorders may be linked to an increased risk of major birth defects, according to a new study. Pregabalin is marketed as Lyrica in the United States and under a number of brand names worldwide. It is approved…Continue readingPregabalin During Pregnancy May Be Linked To Birth Defects

Discovery May Lead To Vaccine For CMV Birth Defect Virus

Scientists believe they may be a step closer to developing a vaccine for congenital cytomegalovirus (CMV), one of the world’s leading infectious causes of birth defects. Researchers have been frustrated in their efforts to develop a vaccine to protect against infections, most notably because of a lack of animal models…Continue readingDiscovery May Lead To Vaccine For CMV Birth Defect Virus