biomarker

A new technique to analyze biochemical changes unique to Huntington’s disease has been developed by researchers at the universities of Southampton and Cambridge. The breakthrough[1] has the potential to lead to the improved diagnosis of disease onset and possibly better ways to track the effects of new treatments. Huntington’s disease damages nerve cells in the… Read more

  We all experience pain, yet there is no objective way to measure it. The best we can do is to ask what it feels like on a 10-point pain scale. But one person’s pain can be another’s slight discomfort. “It’s really subjective. What we really need are biomarkers that allow us to understand the… Read more

A subtype of schizophrenia is related to abnormally high levels hydrogen sulfide in the brain, report researchers at the RIKEN Center for Brain Science who worked with model mice, postmortem human brains, and people with schizophrenia. Experiments showed that this abnormality likely results from a DNA-modifying reaction during development that lasts throughout life. In addition… Read more

The walking speed of 45-year-olds, especially their fastest walking speed without running, can be useful as a marker of their aging brains and bodies, new research from Duke University[1] suggests. Slower walkers were shown to have “accelerated aging” on a 19-measure scale devised by researchers, and their lungs, teeth and immune systems tended to be… Read more

Depression symptoms in cognitively healthy older individuals together with brain amyloid, a biological marker of Alzheimer’s, could trigger changes in memory and thinking over time, researchers from Massachusetts General Hospital (MGH) report. “Our research found that even modest levels of brain amyloid deposition can impact the relationship between depression symptoms and cognitive abilities. This raises… Read more