Scientists from the University of Leicester have for the first time created a detailed image of a toxin called pneumolysin, associated with deadly infections such as bacterial pneumonia, meningitis and septicaemia. The three-year study is an exciting advance because it points to the possibility of creating therapeutics that block assembly of pneumolysin pores to treat… Read more

MIT researchers have developed a biomedical imaging system that could ultimately replace a $100,000 piece of a lab equipment with components that cost just hundreds of dollars. The system uses a technique called fluorescence lifetime imaging, which has applications in DNA sequencing and cancer diagnosis, among other things. So the new work could have implications… Read more

For Harvard neurobiologist Jeff Lichtman, the question hasn’t been whether scientists will ever understand the brain, but how closely they’ll have to look before they do. The answer, it turns out, is very, very close. Led by Lichtman, the Jeremy R. Knowles Professor of Molecular and Cellular Biology and Santiago Ramón y Cajal Professor of… Read more

A University of Maryland-led team of researchers has developed an optical microscopy technique capable of shedding new light on how the mechanical properties of cells change in the course of aging, injury healing and disease pathogenesis. The technique offers promise that one day researchers will be able to identify a more exact starting point for… Read more

One of the holy grails of bio-imaging is to visualize the inner workings of a cell while it is still alive. But this also means that living cells put under the microscope risk being killed by the light and the fluorescent dyes used to highlight their structures. Much like being sunburnt, live cells are sensitive… Read more