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Pneumolysin Toxin’s Detailed Make-up Seen For First Time

Scientists from the University of Leicester have for the first time created a detailed image of a toxin called pneumolysin, associated with deadly infections such as bacterial pneumonia, meningitis and septicaemia. The three-year study is an exciting advance because it points to the possibility of creating therapeutics that block assembly of pneumolysin pores to treat […]

Biomedical Imaging At One-thousandth The Cost

MIT researchers have developed a biomedical imaging system that could ultimately replace a $100,000 piece of a lab equipment with components that cost just hundreds of dollars. The system uses a technique called fluorescence lifetime imaging, which has applications in DNA sequencing and cancer diagnosis, among other things. So the new work could have implications […]

Nanoscale Imaging Of Cleared Brain Tissue

For Harvard neurobiologist Jeff Lichtman, the question hasn’t been whether scientists will ever understand the brain, but how closely they’ll have to look before they do. The answer, it turns out, is very, very close. Led by Lichtman, the Jeremy R. Knowles Professor of Molecular and Cellular Biology and Santiago Ramón y Cajal Professor of […]

Brillouin Microscopy Illuminates Cell Changes Caused By Aging

A University of Maryland-led team of researchers has developed an optical microscopy technique capable of shedding new light on how the mechanical properties of cells change in the course of aging, injury healing and disease pathogenesis. The technique offers promise that one day researchers will be able to identify a more exact starting point for […]