The three proteins Teneurin, Latrophilin and FLRT hold together and bring neighboring neurons into close contact, enabling the formation of synapses and the exchange of information between the cells. In the early phase of brain development, however, the interaction of the same proteins leads to the repulsion of migrating nerve cells, as researchers from the… Read more

A protein that regulates the growth of axons by pulling a brake has been identified by scientists from the German Center for Neurodegenerative Diseases (DZNE). Their findings[1] could one day help to develop new approaches for the treatment of spinal cord injuries. Neurons transmit electrical signals in a clearly defined direction – they are said… Read more

A group of proteins that help to regenerate damaged nerve cells has been identified by scientists at the German Center for Neurodegenerative Diseases (DZNE). It is commonly accepted that neurons of the central nervous system shut down their ability to grow when they no longer need it; this occurs normally after they have found their… Read more

The same mechanism by which damaged peripheral nerves can regenerate after an injury could be activated in cells of the central nervous system – after a spinal cord injury, for instance, new research indicates. “An injury in the peripheral nervous system quickly triggers the activation of a fascinating repair process that allows the injured nerve… Read more

Motor neurons receive a multitude of cues to successfully navigate to their destinations in the body, report Salk Institute scientists. “There are 100 trillion connections in the nervous system governed by 20,000 genes, of which roughly 10 gene families are known to be involved in controlling axon guidance. We wanted to understand the clever genetic… Read more