autism

A unique pattern of DNA damage that arises in brain cells derived from individuals with a macrocephalic form of autism spectrum disorder (ASD) has been uncovered by researchers at the Salk Institute. The finding helps explain what might go awry in the brain during cell division and development to cause the disorder. “Division, or replication… Read more

Researchers believe that autism is caused by mutations that occur sporadically in the egg or sperm or during pregnancy. Activity-dependent neuroprotective protein (ADNP) is a dominant gene whose de novo (during pregnancy) mutations are known to cause autism-related intellectual disabilities. A new Tel Aviv University study has found that ADNP mutations continue to occur in… Read more

It’s 25 years since the fourth edition of the Diagnostic and Statistical Manual (DSM-IV) was published. The manual is the clinical “bible” that defines the criteria for the diagnosis of psychiatric and neurodevelopmental conditions, and was a landmark document for autism spectrum disorder. The first mention of autism came in the third edition of the… Read more

Do people with autism have differently organized brains? A large-scale MRI study reports fewer differences between the right and left hemispheres in people with an autism spectrum disorder. An international team, led by scientists from the Max Planck and Donders institutes in Nijmegen, the Netherlands, and the University of Southern California, found differences in brain… Read more

Exposure to acetaminophen during pregnancy may raise a child’s risk for attention deficit/hyperactivity disorder and autism spectrum disorder, suggests a study from Johns Hopkins University. Researchers analyzed data from the Boston Birth Cohort, a long-term study of factors influencing pregnancy and child development. They collected umbilical cord blood from 996 births and measured the amount… Read more