asthma

More than 100 genetic risk factors that explain why some people suffer from asthma, hay fever and eczema have been identified in a major new international study. Dr Manuel Ferreira, who led the work, said this was the first study designed specifically to find genetic risk factors that are shared among the three most common… Read more

A cell-based therapy for treating lung tissue damaged by respiratory diseases is showing promise in early stage trials, scientists at Imperial College London and Hong Kong University report. The stem cells can reduce some of the damage seen in human lung cells exposed to cigarette smoke in the lab, as well as reducing similar effects… Read more

The molecular mechanism underlying corticosteroid resistance in patients with severe asthma has been uncovered by researchers. They also found that the drug — the main treatment for asthma — may make the condition worse for these patients. Asthma is a lifelong disorder characterized by airway inflammation that leads to wheezing, breathlessness, and coughing. It affects… Read more

A protein that seems to play a vital role in airway function is absent in people who have asthma, according to new research. The finding points to a potential new treatment. When the protein, called SPLUNC1, is low or missing, people experience airway constriction, mucus production, chest tightness, and breathing problems. Robert Tarran, associate professor… Read more

In an entirely new approach to treating asthma and allergies, a biodegradable nanoparticle acts like a Trojan horse, hiding an allergen in a friendly shell, to convince the immune system not to attack it, according to new Northwestern Medicine research. As a result, the allergic reaction in the airways is shut down long- term and… Read more