Why SSRI Anti-depressants Cause Emotional Numbing

Credit: Langley, C., Armand, S., Luo, Q. et al. CC-BY

Scientists have discovered why common antidepressants cause approximately half of their users to feel emotionally “blunted.” According to a new study, the drugs have an effect on reinforcement learning, an important behavioural process that allows people to learn from their surroundings. Selective serotonin reuptake inhibitors (SSRIs) are a popular class of antidepressants, especially for chronic…

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Amygdala Scans Useful for Predicting Recovery on Antidepressants

Amygdala highlighted in pink. Credit: Westmead Institute for Medical Research

Combining new brain scan techniques with patient information about any early life trauma can predict with unprecedentedly high (80%) accuracy whether a depressed patient is likely to recover with anti-depressant medications (ADM), or not, a team of Australian and United States mental health researchers has found. The ability to predict ADM response is important because,…

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