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Targeting GABA Receptors With Neurosteroids In Depression

A neurosteroids approach to alleviate depression, using CRISPR technology, is being investigated by researchers at Washington University School of Medicine in St. Louis and Sage Therapeutics in Boston. Most antidepressant drugs target serotonin receptors, aiming to boost serotonin, a chemical thought to regulate mood and social behavior. Using gene editing, the scientists have been able […]

Do Antidepressants Really Double Risk Of Suicide?

The Daily Telegraph reports that “Antidepressants could double the risk of feelings that could lead to suicide, according to a new study which has triggered furious rows.” Critics have attacked the study as “fatally flawed” because researchers extrapolated certain side effects, such as anxiety, as being a risk factor for suicide.┬áResearchers carried out an analysis […]

Majority Of Antidepressants Ineffective For Kids or Teens, Study Shows

Most antidepressants prescribed for children and teenagers with major depression are ineffective, and could even be unsafe, a major review shows. The comprehensive review found that of 14 antidepressant drugs, only fluoxetine (Prozac) was more effective at relieving the symptoms of depression than a placebo. Taking venlafaxine (Effexor) was linked with an increased risk of […]

New Anti-depressant Compounds May Work Fast, Have Few Side Effects

New compounds that could effectively treat depression in less than 24 hours, while curtailing side effects, have been identified. The compounds, according to a new study by researchers at University of Maryland School of Medicine, could offer significant advantages over current antidepressant medications, even though they have not yet been tested in people. Research leader […]