A previously unknown gene and associated protein which could potentially be suppressed to slow the advance of Alzheimer’s disease have been identified by researchers at Case Western University School of Medicine. “Based on the data we have, this protein can be an unrecognized new risk factor for Alzheimer’s disease (AD). We also see this as… Read more

Vasomotion, the spontaneous oscillation in tone of blood vessel walls, independent of heart beat, innervation or respiration, pushes the clearance of substances from the brain, investigators at Massachusetts General Hospital (MGH) have found. The findings suggest that targeting and enhancing this process may promote prevention or treatment of amyloid-beta accumulation. In Alzheimer’s disease, amyloid-beta protein… Read more

Inflammation drives the progression of neurodegenerative brain diseases and plays a major role in the accumulation of tau proteins within neurons, research indicates[1]. The findings, from an international research team led by the German Center for Neurodegenerative Diseases (DZNE) and the University of Bonn, are based on the analyses of human brain tissue and further… Read more

The link between amyloid beta and tau may lie in the brain’s immune cells that hem in clumps of amyloid, researchers at Washington University School of Medicine in St. Louis have found. If the immune cells falter, amyloid clumps, or plaques, injure nearby neurons and create a toxic environment that accelerates the formation and spread… Read more

Viruses interact with proteins in the biological fluids of their host which results in a layer of proteins on the viral surface, new research from Stockholm University and Karolinska Institutet shows. This coat of proteins makes the virus more infectious and facilitates the formation of plaques characteristic of neurodegenerative diseases such as Alzheimer’s disease. “Imagine… Read more