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The Self In Dementia Is Not Lost, And Can Be Reached With Care

Many people see memory as providing the foundation upon which a stable sense of self is constructed. Our autobiographical memory, in particular, seems crucial to weaving a life story that bridges past and present, and permits us to extrapolate how the future might unfold, all within a meaningful and coherent narrative. So what happens when […]

Alzheimer’s Subtypes Could Affect Future Treatments

A team of neuroscientists at Mayo Clinic in Florida examined a vital region of the brain and found that patterns of Alzheimer’s-related damage differed by subtype and age of onset. The researchers say these observations could have important treatment implications. “Alzheimer’s affects people in different ways. If we learn why it will help us untangle […]

MRI May Prevent Alzheimer’s Misdiagnosis In Seniors With Memory Loss

With the use of MRI scans, it is possible to distinguish between memory loss caused by Alzheimer’s disease and traumatic brain injury, according to a UCLA-led study. The finding[1] is important because it could help prevent a misdiagnosis of Alzheimer’s disease, which can be devastating for patients and their families. A previous study found that […]

Neural Activity Plays A Role In Human Aging And Life Span

The brain’s neural activity – long implicated in disorders ranging from dementia to epilepsy – also plays a role in human aging and life span, according to research led by scientists in the Blavatnik Institute at Harvard Medical School. The findings¬†offer the first evidence that the activity of the nervous system affects human longevity. Although […]

Tau-mediated RNA Splicing Errors Linked To Alzheimer’s Disease

A novel mechanistic link between alterations in RNA splicing and tau-mediated neurodegeneration in Alzheimer’s disease us reported in a collaborative study in the journal Cell Reports[1]. The study, led by researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, integrates data from human brain autopsy […]