Alzheimer’s Disease Destroys Neurons That Keep Us Awake

Researchers and caregivers have noted that excessive daytime napping can develop long before the memory problems associated with Alzheimer's disease begin to unfold. Prior studies have considered this excessive daytime napping to be compensation for poor nighttime sleep caused by Alzheimer's-related disruptions in sleep-promoting brain regions, while others have argued that the sleep problems themselves …

Depression Symptoms In Alzheimer’s Could Be Signs For Cognitive Decline

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Depression symptoms in cognitively healthy older individuals together with brain amyloid, a biological marker of Alzheimer's, could trigger changes in memory and thinking over time, researchers from Massachusetts General Hospital (MGH) report. "Our research found that even modest levels of brain amyloid deposition can impact the relationship between depression symptoms and cognitive abilities. This raises …

Blood Test Is 94% Accurate At Identifying Early Alzheimer’s Disease

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Up to two decades before people develop the characteristic memory loss and confusion of Alzheimer's disease, damaging clumps of protein start to build up in their brains. Now, a blood test to detect such early brain changes has moved one step closer to clinical use. Researchers from Washington University School of Medicine in St. Louis …

Altered Liver Enzymes Associated With Biomarkers For Alzheimer’s Disease

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Novel connections between liver dysfunction and Alzheimer's disease have been identified in research from the Alzheimer's Disease Metabolomics Consortium (ADMC) and Alzheimer's Disease Neuroimaging Initiative (ADNI). The study, was led by IU School of Medicine radiology professor Kwangsik Nho, Ph.D. and explores the relationship between blood-based biochemical markers of liver function and established Alzheimer's disease …

Super-resolution Microscopy Sheds Light On How Dementia Protein Becomes Dysfunctional

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Super-resolution microscopy was used by University of Queensland researchers to observe key molecules at work inside living brain cells, further unravelling the puzzle of memory formation and the elusive causes of dementia. "One of the distinguishing features of Alzheimer's disease is the tangles of Tau protein that form inside brain cells, but this is the …

Alzheimer’s Gene APOE May Effect Cognition Before Adulthood

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A gene associated with Alzheimer’s disease may have an impact on cognitive health much sooner than previously realized, new research suggests. The APOE gene creates a protein, apolipoprotein E, which packages cholesterol and other fats to transport them through the bloodstream. There are three versions, or alleles, of APOE. One of those is the APOE4 …

Alzheimer’s Family History Associated With Impaired Learning

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Adults having a close relative with Alzheimer's disease do more poorly in online paired-learning tasks than adults without such a family history, new research has found. Additionally, this impairment appears to be worsened by having diabetes or a genetic variation in the apolipoprotein E (APOE) gene linked to the disease. The findings may help identify …