Among people who have the most common type of lung cancer, up to 40% develop metastatic brain tumors, with an average survival time of less than six months. But why non-small-cell lung cancer so often spreads to the brain has been poorly understood. Now scientists at Wake Forest School of Medicine have found that nicotine, a non-carcinogenic chemical found in tobacco, actually promotes the spread, or metastasis, of lung cancer cells into the brain.
The human brain is bathed in a supportive fluid called the cerebrospinal fluid (CSF) that provides nutrients and is required for proper brain function. The composition of human CSF and how it is made are poorly understood due to a lack of experimental access. Madeline Lancaster’s group in the Medical Research Council of England’s Laboratory of Molecular Biology Cell Biology Division has now developed a new brain organoid that produces CSF and has the potential to predict whether drugs can access the brain.
Social neuroscience researchers at Aalto University investigated the effects of similarity by showing subjects the film My Sister’s Keeper and asking them to watch the film from either the perspective of the donor sister or the sick sister. The subjects' brain processing was measured by functional MRI, and at the same time eye tracking was carried out, monitoring where the subject’s eyes were looking on the screen. “Understanding another person’s point of view is important to reach consensus.
Our most vivid dreams are a remarkable replication of reality, combining disparate objects, actions and perceptions into a richly detailed hallucinatory experience. How does our brain accomplish this? It has long been suspected that the hippocampus contributes to dreaming, in part due to its close association with memory: according to one estimate, about half of all dreams contain at least one element originating from a specific experience while the subject was awake (Fosse et al.
People suffering from post-traumatic stress disorder report that cannabis reduces the severity of their symptoms by more than half, at least in the short term, according to a recent study led by Carrie Cuttler, a Washington State University assistant professor of psychology. Cuttler and her colleagues analyzed data of more than 400 people who tracked changes in their PTSD symptoms before and after cannabis use with Strainprint, an app developed to help users learn what types of medical cannabis work best for their symptoms.
The development of a 2D nanosheet 1,000 times smaller than a strand of hair could advance cancer treatment and regenerative medicine, say researchers. The new class of 2D nanosheets called molybdenum disulfide can adsorb near infrared (NIR) light and modify cell behavior. These nanosheets are an emerging class of materials that have shown distinct physical and chemical properties due to their unique shape and size. Recently, some nanosheets have been explored for biomedical applications due to their light-responsive ability.
If a two-year-old child living in poverty in India or Bangladesh gets sick with a common bacterial infection, there is more than a 50% chance an antibiotic treatment will fail. Somehow the child has acquired an antibiotic resistant infection – even to drugs to which they may never have been exposed. How? Unfortunately, this child also lives in a place with limited clean water and less waste management, bringing them into frequent contact with faecal matter.
Psychiatric patients with higher levels of an antioxidant called glutathione responded more quickly to medication for psychosis and had improved outcomes, a study from Schulich and Lawson Health Research Institute reports. Once patients with psychosis start treatment, some get better in weeks while it can take months for others. Past research has shown that patients who experience their first episode of psychosis and respond early to treatment have better overall outcomes.