Prepronociceptin Neurons Help Drive Physiological Reactions To Fear And Anxiety

A population of brain cells whose activity appears to drive physiological arousal responses to strong emotions such as fear and anxiety has been identified by scientists at University of North Carolina. They found that artificially forcing the activity of these brain cells in mice produced an arousal response in the form of dilated pupils and faster heart rate, and worsened anxiety-like behaviors. Focusing on arousal responses might offer a new way to intervene in psychiatric disorders,

Prazosin Moderates Drinking For People With Alcohol Withdrawl

Prazosin, a drug once used to treat high blood pressure, can help alcoholics who are experiencing withdrawal symptoms to reduce or eliminate their drinking, researchers report. There has been no treatment readily available for people who experience severe withdrawal symptoms and these are the people at highest risk of relapse and are most likely to end up in hospital emergency rooms,” said Rajita Sinha, a professor of psychiatry and neuroscience, director of the Yale University Stress Center, and corresponding author of the paper1.

Fluvoxamine May Avert Serious Complications From Covid

The antidepressant fluvoxamine seems to restrain some of the more serious complications of COVID-19, reports a study of adult outpatients with mild-to-moderate symptoms.1 Researchers say the drug also appeared to lower the chances for them requiring supplemental oxygen and hospitalization. The patients who took fluvoxamine did not develop serious breathing difficulties or require hospitalization for problems with lung function. Most investigational treatments for COVID-19 have been aimed at the very sickest patients, but it’s also important to find therapies that prevent patients from getting sick enough to require supplemental oxygen or to have to go to the hospital.

MEC-RSC Neural Pathway Signals Landmark Coding For Spatial Navigation

Researchers at the Max Planck Institute for Brain Research and Goethe University Frankfurt have uncovered a neural pathway in the rodent brain that may play a key role in processing spatial perspectives and help the animal to detect boundaries to avoid bumping into things. Animals use landmarks in the environment as a reference point to identify the self’s position and navigate their surroundings. In rodents, this ability is supported by very specialized types of neurons, including place cells and grid cells, that fire only when the animal is at a precise location in the environment, even in an open arena,

Spatial Perception In Hearing Is Linked With Interaural Time Difference

When you hear a sound, how do your senses figure out what direction it is coming from? A sound coming from your right will reach your right ear a few fractions of a millisecond earlier than your left ear. The brain uses this difference, known as the interaural time difference (ITD), to locate the sound. But we are also significantly better at locating sounds that come from in front of us than from sources at our sides.

Social Interaction: Constructing Empathy And Perspective Taking

A model explaining how empathy and perspective taking are constructed by the brain has been developed by researchers1. Numerous studies have been conducted that examine empathy and perspective taking (also known as “theory of mind”) as a whole. However, what constitutes the core of both competencies and where in the brain their bases lie has not yet been clarified. Both of these abilities are processed in the brain by a main network specialised in empathy or changing perspective, which is activated in every social situation.

Astrocytes Play Role In Maintaining Brain pH Balance

Astrocytes play an important role in preventing acidification of the brain, a new study in mice led by University College London researchers reports. The researchers hope their findings1 will help further understanding of several common brain diseases that involve disturbances of pH balance. These include stroke and epilepsy. The human brain consumes an immense amount of energy, the rate of which is estimated to be equal to human leg muscles running a marathon.

Pupils Show If People Will Remember Or Forget Something

Researchers can now predict whether an individual will remember or forget based on their neural activity and pupil size. As we navigate our lives, we have these periods in which we’re frustrated because we’re not able to bring knowledge to mind, expressing what we know. Fortunately, science now has tools that allow us to explain why an individual, from moment to moment, might fail to remember something stored in their memory,