Ketamine has gotten a bad rap as an opioid when there’s plenty of evidence suggesting it isn’t one, Johns Hopkins experts say. They believe this reputation may hamper patients from getting necessary treatment for the kinds of depression that don’t respond to typical antidepressants. In a new paper, the researchers clarify the mechanism behind ketamine’s… Read more

Cannabidiol reduces the aggressiveness induced by social isolation, a new study finds. The research, based on a mouse model, was conducted by scientists at the University of São Paulo’s Ribeirão Preto Medical School (FMRP-USP). “Our study shows that cannabidiol can inhibit aggressiveness and that it does so by facilitating the activation of two receptors: the… Read more

The benefits of a specific psychotherapeutic approach may disappear after two years from the conclusion of the psychotherapy, a new study indicates. Evidence on the long-term efficacy of psychotherapeutic approaches for chronic depression is scarce. The goal of the trial was to evaluate the effects of the Cognitive Behavioral Analysis System of Psychotherapy (CBASP) compared… Read more

Dissociative disorders are often said to be rare. But our soon-to-be published analysis of international studies suggest they affect 10-11% of the population at some point in their lives. This makes them nearly as common as mood disorders (such as clinical depression). So what are dissociative disorders, why is diagnosis controversial and how can people… Read more

When someone is depressed and having suicidal thoughts or their depression treatment just isn’t working, their caregivers might want to check to see if they have obstructive sleep apnea, investigators say. That’s true even when these individuals don’t seem to fit the usual profile of obstructive sleep apnea, which includes males who are overweight, snore… Read more