Neurology

Protein clusters thought to be tied to amyotrophic lateral sclerosis (ALS) may actually protect, rather than harm, neurons. Autopsy studies of ALS patients often reveal the accumulation of large, fibrous aggregates of a protein called SOD1 in disease-affected motor neurons. Researchers have hypothesized that these fibrils are what kill neurons and cause ALS in some… Read more

People diagnosed with a mild concussion, or mild traumatic brain injury, could have a 56 percent increased risk of developing Parkinson’s disease, according to a new study. Moderate to severe traumatic brain injury was defined as a loss of consciousness for more than 30 minutes, alteration of consciousness of more than 24 hours or amnesia… Read more

Slightly elevated beta-amyloid levels in the brain are associated with increased activity in certain brain regions, a new study from the Center for Vital Longevity (CVL) at The University of Texas at Dallas reports. But that increase in activity might not be such a positive thing. The results indicate that the brains of these individuals… Read more

Amyloid beta, the protein linked with Alzheimer’s disease, has different properties in different cell types in the brains of fruit flies, a study led by researchers at Linköping University in Sweden indicates. Although amyloid beta is highly toxic for nerve cells, it appears that certain other types of cell are unaffected by aggregates of the… Read more

Inflammatory reactions can alter the brain’s immune cells in the long term — meaning that these cells have an “immunological memory.” This memory may influence the progression of neurological disorders that occur later in life, and is therefore a previously unknown factor that could influence the severity of these diseases, scientists at the German Center… Read more