How Neurons Adjust Excitation-Inhibition Balance Unaided

A mechanism by which neurons can regulate their sensitivity to incoming signals autonomously has been discovered in a new study led by the University of Bonn. The researchers, including those from the German Center for Neurodegenerative Diseases and the Max Planck Institute for Neurobiology of Behavior, investigated pyramidal neurons – nerve cells that also play…

Urban Green Space 3-30-300 Rule Mental Health Benefits Tested

Longer life expectancy, fewer mental health issues, and improved cognitive functioning are just a few of the many well-known health advantages of urban green space. The amount of green space required, however, to improve people’s health is still up for debate. The 3-30-300 green space rule and better mental health have been compared in a…

Adverse Childhood Experiences Significantly Impact Physical and Mental Health

The social environments we grow up in are very important to our health and happiness as adults. Most Americans (67%) say they went through at least one traumatic event when they were young. A new study using phenome-wide association analyses shows that these events have a big effect on our health risks as adults. Obesity…

Genetic Mechanism Of Dopamine In Schizophrenia Identified

Schizophrenia is a devastating brain disorder characterized by delusional thinking, hallucinations, and other forms of psychosis; how the brain chemical dopamine relates to this disorder has been a mystery for more than 70 years, but researchers at the Lieber Institute for Brain Development (LIBD) believe they have found an answer. Scientists identified the genetic mechanism…

Kinesin-5 Gene May Protect Against Alzheimer’s Disease

According to a new study, cognitive decline in both mice and humans with Alzheimer’s disease (AD) may be protected by the overexpression of a gene linked to cell division and the structure and function of neurons. The gene Kinesin-5 or KIF11 accomplishes this despite the fact that amyloid beta, the main component of plaques in…

Ketamine Vs Electroshock Therapy – ECT More Effective Depression Treatment

A new meta-analysis has shown that electroconvulsive therapy (ECT) is better at quickly relieving major depression than ketamine. Most of the time, a person with depression is first prescribed an oral antidepressant medication, along with psychotherapy. But if oral antidepressants don’t work or if the person is in danger of hurting themselves right away, there…

Medulla Oblongata Function and Location

The medulla oblongata or simply medulla is a long stem-shaped brain structure which comprises the lower section of the brainstem. It is in front of and partly under the cerebellum. The cardiac, respiratory, vomiting and vasomotor nerve centers are contained in the medulla. Consequently, it handles the autonomic functions of breathing, heart rate and blood…

CRISPR/Cas9 Editing Can Cause Genome Instability And Cell Toxicity

Depending on the targeted spot of the human genome, CRISPR gene editing can give rise to cell toxicity and genomic instability, Barcelona Institute for Research in Biomedicine scientists report1. CRISPR/Cas9 is a gene editing technique whose developers were the subject of the 2020 Nobel Prize in Chemistry. This adverse effect involves the linchpin tumour suppressor…